Chemistry, physiological properties, and microbial production of hydroxycitric acid

@article{Yamada2007ChemistryPP,
  title={Chemistry, physiological properties, and microbial production of hydroxycitric acid},
  author={Takashi Yamada and Hiroyuki Hida and Yasuhiro Yamada},
  journal={Applied Microbiology and Biotechnology},
  year={2007},
  volume={75},
  pages={977-982}
}
The tropical plants Garcinia cambogia and Hibiscus subdariffa produce hydroxycitric acid (HCA), of which the absolute configurations are (2S,3S) and (2S,3R), respectively. (2S,3S)-HCA is an inhibitor of ATP-citrate lyase, which is involved in fatty acid synthesis. (2S,3R)-HCA inhibits pancreatic α-amylase and intestinal α-glucosidase, leading to a reduction in carbohydrate metabolism. In this study, we review current knowledge on the structure, biological occurrence, and physiological… 
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