Cheminformatic Analysis of Antimalarial Chemical Space Illuminates Therapeutic Mechanisms and Offers Strategies for Therapy Development.

Abstract

The clear and present danger of malaria, which has been amplified in recent years by climate change, and the progressive thinning of our drug arsenal over the past two decades raise uncomfortable questions about the current state and future of antimalarial drug development. Besides suffering from many of the same technical challenges that affect drug… (More)
DOI: 10.1021/acs.jcim.7b00072

Cite this paper

@article{Varela2017CheminformaticAO, title={Cheminformatic Analysis of Antimalarial Chemical Space Illuminates Therapeutic Mechanisms and Offers Strategies for Therapy Development.}, author={Julia Nogueira Varela and Mar{\'i}a Fernanda Lammoglia Cobo and Sandip V. Pawar and Vikramaditya G Yadav}, journal={Journal of chemical information and modeling}, year={2017}, volume={57 9}, pages={2119-2131} }