Chemically induced hypoglycemia and anoxia: relationship to glutamate receptor-mediated toxicity in retina.

Abstract

Chemically induced hypoglycemia and anoxia were evaluated in embryonic day 13 chicken retina to determine if excitotoxicity was a consequence of these conditions and if this was preceded by the net release of glutamate or aspartate. Retina incubated with iodoacetate (IOA), to inhibit glycolysis, or potassium cyanide (KCN), to inhibit electron transport… (More)

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