Chemically induced esthesioneuroepithelioma: a cytogenetic, cell culture and biochemical investigation with implications for tumor histogenesis

Abstract

Chemically induced esthesioneuroepitheliomas (ENE) in rats were subjected to tissue culture experiments, biochemical evaluations for catecholamines and chromosomal analyses. The most conspicuous cytogenetic finding was a C1 marker chromosome in addition to numerical and structural chromosomal aberrations. Regarding the overwhelming similarity between human… (More)
DOI: 10.1007/BF00457457

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