Chemically imaging living cells by scanning electrochemical microscopy.

  title={Chemically imaging living cells by scanning electrochemical microscopy.},
  author={Allen J Bard and Xiao Li and Wei Zhan},
  journal={Biosensors & bioelectronics},
  volume={22 4},
Scanning electrochemical microscopy (SECM) is useful in probing and characterizing interfaces at high resolution. In this paper, the general principles of this technique are described and several applications of SECM to biological systems, particularly to living cells, is discussed, along with several example systems. Thiodione was detected and monitored electrochemically during the treatment of hepatocytes with cytotoxic menadione. The antimicrobial effects of silver(I) was followed by SECM… CONTINUE READING