Chemically controlled closed-loop insulin delivery.

  title={Chemically controlled closed-loop insulin delivery.},
  author={Val{\'e}rie Ravaine and Christophe Ancla and Bogdan Catargi},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  volume={132 1},
Alternative treatments for diabetes are currently being investigated to improve both patient comfort and avoid complications due to hyperglycaemia episodes. In the absence of a cure like pancreas or beta-islets transplants, the ideal method would be an artificial "closed-loop" system able to mimic pancreas activity. This would operate continuously and automatically, causing appropriate response to losses and gains in glucose levels. Chemically controlled closed-loop insulin delivery has been… CONTINUE READING


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