Chemically Induced Cryptic Sesquiterpenoids and Expression of Sesquiterpene Cyclases in Botrytis cinerea Revealed New Sporogenic (+)-4-Epieremophil-9-en-11-ols.

@article{Pinedo2016ChemicallyIC,
  title={Chemically Induced Cryptic Sesquiterpenoids and Expression of Sesquiterpene Cyclases in Botrytis cinerea Revealed New Sporogenic (+)-4-Epieremophil-9-en-11-ols.},
  author={Cristina Pinedo and Javier Moraga and J. Bar{\'u}a and V. Gonz{\'a}lez-Rodr{\'i}guez and J. Aleu and R. Dur{\'a}n-Patr{\'o}n and A. J. Mac{\'i}as-S{\'a}nchez and J. R. Hanson and M. Viaud and R. Hern{\'a}ndez-Gal{\'a}n and C. Garrido and I. G. Collado},
  journal={ACS chemical biology},
  year={2016},
  volume={11 5},
  pages={
          1391-400
        }
}
The sequencing of the genomes of the B05.10 and T4 strains of the fungus Botrytis cinerea revealed an abundance of novel biosynthetic gene clusters, the majority of which were unexpected on the basis of the previous analyses of the fermentation of these and closely related species. By systematic alteration of easy accessible cultivation parameters, using chemical induction with copper sulfate, we have found a cryptic sesquiterpenoid family with new structures related to eremophil-9-ene, which… Expand
Biosynthesis of abscisic acid in fungi: identification of a sesquiterpene cyclase as the key enzyme in Botrytis cinerea
The infection cushion: a fungal “weapon” of plant-biomass destruction
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