Chemical requirements for inhibition of gap junction communication by the biologically active lipid oleamide.

@article{Boger1998ChemicalRF,
  title={Chemical requirements for inhibition of gap junction communication by the biologically active lipid oleamide.},
  author={Dale L. Boger and Jean E. Patterson and X. L. Guan and Benjamin F. Cravatt and Richard A Lerner and Norton B. Gilula},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1998},
  volume={95 9},
  pages={
          4810-5
        }
}
Oleamide is an endogenous fatty acid primary amide that possesses sleep-inducing properties in animals and has been shown to effect serotonergic systems and block gap junction communication in a structurally specific manner. Herein, the structural features of oleamide required for inhibition of the gap junction-mediated chemical and electrical transmission in rat glial cells are defined. The effective inhibitors fall into two classes of fatty acid primary amides of which oleamide and… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 40 CITATIONS

Biosynthesis of oleamide.

  • Vitamins and hormones
  • 2009
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Mast cells promote fibroblast populated collagen lattice contraction through gap junction intercellular communication.

  • Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
  • 2004
VIEW 9 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED