Chemical radiculitis

  title={Chemical radiculitis},
  author={Baogan Peng and Wenwen Wu and Zhen-Zhou Li and Ji-dong Guo and Xiaoning Wang},

Use of Autologous Serum in Treatment of Lumbar Radiculopathy Pain. Pilot Study.

  • Piotr Godek
  • Medicine
    Ortopedia, traumatologia, rehabilitacja
  • 2016
The Orthokine therapy conducted under ultrasound guidance may be an interesting option in the treatment of compression radiculopathy in the course of radicular compression due to a herniated disc and provides the rationale for studying larger groups of subjects in controlled studies over longer periods of time.

Diagnosis of discogenic low back pain in patients with probable symptoms but negative discography

The study indicated that negative discography in patients with probable symptoms of discogenic low back pain cannot absolutely exclude the diagnosis ofDiscogenic pain.

Significance of Perianular Enhancement Associated With Anular Tears on Magnetic Resonance Imagings in Diagnosis of Radiculopathy

The perianular enhancement adjacent to anular tears on MRI may be relevant in the diagnosis of symptomatic chemical radiculitis and a reliable imaging method for replacing invasive provocative CT discography and diagnosing chemical Radiculopathy is required.

The Effect of Laser Irradiation for Nucleus Pulposus: an Experimental Study

One of the mechanisms thought to be responsible for PLDD's effectiveness is a decrease in the chemical factors through protein alteration in the intervertebral disc by laser irradiation.

Value of 3D MR Lumbosacral Radiculography in the Diagnosis of Symptomatic Chemical Radiculitis

It is believed that in cases without mechanical nerve root compression caused by disk herniation or stenosis in the lumbar spine, nerve root swelling on 3D MR radiculography in patients withRadiculopathy associated with an anular tear may be relevant in the diagnosis of symptomatic chemical radicULopathy.

Role of caudal epidural steroid injections in the management of chronic low backache

Epidural steroids are slowly proving to be a reliable alternative for all eviating pain and radiculopathy for a short term and provides significant symptom free time for patients to receive physiotherapy that is crucial for early and adequate rehabilitation.

Dor após cirurgia lombar: imagem e reflexos Pain after lumbar surgery: image and reflexes

Most patients with persistent or recurrent pain after lumbar spinal surgery presents with documented anatomical lesion that may justify pain complaints and the negative impact on quality of life makes this clinical picture a true challenge for Physical Medicine and Rehabilitation.

Correlation of Foraminal Area and Response to Cervical Nerve Root Injections

Measurement of neuroforaminal areas on MRI may represent a useful pre-procedural technique to predict which patients with symptoms of cervical radiculopathy secondary to foraminal stenosis are likely to respond to selective nerve root injections.

Transforaminal endoscopic system technique for discogenic low back pain: A prospective Cohort study.




[The pathogenesis of discogenic low back pain].

Findings indicate that the strip zone of granulation tissue with extensive innervation in the posterior part of the painful disc is the original site of the pain of discography and the discogenic low back pain.

Chemical radiculitis. A clinical, physiological and immunological study.

Chemical radiculitis is an inflammatory condition of the nerveRoot due to the rupture of the annulus fibrosus and dissemination of disk fluid along the nerve root sheath, which evokes circulating antibody response and auto immune reaction.

Experimental Disc Herniation: Evaluation of the Natural Course

It is demonstrated for the first time that nucleus pulposus‐induced nerve root injury reverses in 2 months and that it may be present without simultaneous nerve root compression, as confirmed by findings in magnetic resonance imaging.

Pathomechanism of Pain‐Related Behavior Produced by Allografts of Intervertebral Disc in the Rat

The nucleus pulposus and anulus fibrosus produce different forms of hyperalgesia associated with different and distinct immunohistochemical changes, and it is possible that radicular pain of a lumbar disc herniation results from chemicals, such as phospholiapse A2 and nitric oxide.

Possible Mechanism of Painful Radiculopathy in Lumbar Disc Herniation

The authors suggest that chemical mediators such as phospholipase A, and nitric oxide, induced by extruded or sequestrated intervertebral discs, are involved in the pathophysiologic mechanisms of painful radiculopathy in lumbar disc herniations.

Pathomechanisms of Nerve Root Injury Caused by Disc Herniation: An Experimental Study of Mechanical Compression and Chemical Irritation

It was shown that each of the assessed factors induces nerve dysfunction, however, the combination of mechanical compression (mass effect of herniated NP) and chemical irritation (inflammation around nerve root) may induce more nerve root injury than each factor per se.

Intervertebral discs which cause low back pain secrete high levels of proinflammatory mediators.

The high levels of proinflammatory mediator found in disc tissue from patients undergoing fusion suggest that production of pro inflammatory mediators within the nucleus pulposus may be a major factor in the genesis of a painful lumbar disc.

Possible Pathogenesis of Painful Intervertebral Disc Degeneration

The findings indicated that degeneration of the painful disc might originate from the injury and subsequent repair of anulus fibrosus and growth factors, such as bFGF and TGF-&bgr;1, macrophages and mast cells might play a key role in the repair of the injured anulus fibre and subsequent disc degeneration.

Acute Effects of Nucleus Pulposus on Blood Flow and Endoneurial Fluid Pressure in Rat Dorsal Root Ganglia

Approximate observations in the dorsal root ganglia may help to explain why disc herniations without compression of neural tissue are sometimes painful because similar pathologic findings are observed after only nucleus pulposus application to the nerve root.

Effect of Nucleus Pulposus on the Neural Activity of Dorsal Root Ganglion

After application of nucleus pulposus to the nerve root, the dorsal root ganglion demonstrated increased excitability and mechanical hypersensitivity, suggesting that nucleus pulPOSus causes excitatory changes in the dorsal Root Ganglion.