Chemical proteomics-driven discovery of oleocanthal as an Hsp90 inhibitor.

@article{Margarucci2013ChemicalPD,
  title={Chemical proteomics-driven discovery of oleocanthal as an Hsp90 inhibitor.},
  author={Luigi Margarucci and Maria Chiara Monti and Chiara Cassiano and Matteo Mozzicafreddo and Mauro Angeletti and Raffaele Riccio and Alessandra Tosco and Agostino Casapullo},
  journal={Chemical communications},
  year={2013},
  volume={49 52},
  pages={5844-6}
}
Hsp90, a key target in cancer therapy, has been identified as the main partner of oleocanthal, an olive oil bioactive compound. A combination of chemical and biological assays disclosed its mechanism of action at the molecular level. 

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