Chemical protection against gastrointestinal radiation injury in mice by WR 2822, WR 2823, or WR 109342 after 4 MeV X ray or fission neutron irradiation.

@article{Connor1982ChemicalPA,
  title={Chemical protection against gastrointestinal radiation injury in mice by WR 2822, WR 2823, or WR 109342 after 4 MeV X ray or fission neutron irradiation.},
  author={A. Connor and C. Sigdestad},
  journal={International journal of radiation oncology, biology, physics},
  year={1982},
  volume={8 3-4},
  pages={
          547-51
        }
}
  • A. Connor, C. Sigdestad
  • Published 1982
  • Medicine
  • International journal of radiation oncology, biology, physics
  • Three compounds were tested for their radioprotective properties against the effects of 4 MeV X rays or fission neutron irradiation. The endpoints tested were lethality, intestinal crypt survival, and DNA synthesizing cellularity. Two of the compounds tested; S-2(4-aminobutylamino) ethylphosphorothioic acid (WR 2822) and the aminopentylamino derivative (WR 2823) are closely related to WR 2721. The third agent was the iminothiol derivative of 1-methyl-aminoadamantine (WR 109342). All drugs were… CONTINUE READING
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