Chemical, physical, and biologic properties of biosynthetic human insulin.


Human insulin derived via recombinant DNA technology was tested extensively by a complex battery of analytic procedures. This product, which is designated biosynthetic human insulin, was found to be chemically, physically, and immunologically equivalent to pancreatic human insulin and biologically equivalent to both pancreatic human insulin and purified pork insulin.

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@article{Chance1981ChemicalPA, title={Chemical, physical, and biologic properties of biosynthetic human insulin.}, author={Ronald E. Chance and E P Kroeff and James A. Hoffmann and Bruce H. Frank}, journal={Diabetes care}, year={1981}, volume={4 2}, pages={147-54} }