Chemical nucleases as probes for studying DNA-protein interactions.

  title={Chemical nucleases as probes for studying DNA-protein interactions.},
  author={Athanasios G. Papavassiliou},
  journal={The Biochemical journal},
  volume={305 ( Pt 2)},
  • A. Papavassiliou
  • Published 15 January 1995
  • Biology, Chemistry
  • The Biochemical journal
Over the past fifteen years much research has been devoted to the mode(s) by which the linear DNA macromolecule communicates with cellular proteins in the course of genetic programming, thus determining the patterns of growth and development in living organisms. A plethora of proteins have been shown to interact non-covalently with DNA either as structural elements, exemplified by the histones of eukaryotic chromatin, or as components of the complex cellular machineries operating in the… 

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EMBO J . 7 , 1871 - 1879 48
  • 1988