Chemical deamidation: a common pitfall in large-scale N-linked glycoproteomic mass spectrometry-based analyses.

@article{Palmisano2012ChemicalDA,
  title={Chemical deamidation: a common pitfall in large-scale N-linked glycoproteomic mass spectrometry-based analyses.},
  author={Giuseppe Palmisano and Marcella Nunes Melo-Braga and Kasper Engholm-Keller and Benjamin L. Parker and Martin R Larsen},
  journal={Journal of proteome research},
  year={2012},
  volume={11 3},
  pages={1949-57}
}
N-Linked glycoproteins are involved in several diseases and are important as potential diagnostic molecules for biomarker discovery. Therefore, it is important to provide sensitive and reliable analytical methods to identify not only the glycoproteins but also the sites of glycosylation. Recently, numerous strategies to identify N-linked glycosylation sites have been described. These strategies have been applied to cell lines and several tissues with the aim of identifying many hundreds (or… CONTINUE READING