Chemical constituents of the soft corals Sinularia vanderlandi and Sinularia gravis from the coast of Madagascar.
@article{Rahelivao2016ChemicalCO, title={Chemical constituents of the soft corals Sinularia vanderlandi and Sinularia gravis from the coast of Madagascar.}, author={Marie Pascaline Rahelivao and Margit Gruner and Tilo L{\"u}bken and Daut R. Islamov and Olga N. Kataeva and Hanta Andriamanantoanina and Ingmar Bauer and Hans‐Joachim Kn{\"o}lker}, journal={Organic \& biomolecular chemistry}, year={2016}, volume={14 3}, pages={ 989-1001 } }
The crude extracts of the Madagascan soft corals Sinularia vanderlandi and Sinularia gravis (Alcyoniidae) showed activity against Plasmodium falciparum which led us to study their chemical constituents. The new cadinane-type sesquiterpenoid vanderlandin (1) has been obtained from S. vanderlandi along with 24-methylenecholesterol (2). Four new compounds, the spatane-type diterpenoid gravilin (3), the monoalkylmonoacylglycerol 4, the dihomoditerpenoid ketone 5, and isodecaryiol (9), along with…
Figures from this paper
12 Citations
Isolation and structure elucidation of natural products of three soft corals and a sponge from the coast of Madagascar.
- ChemistryOrganic & biomolecular chemistry
- 2017
The extracts of all three soft corals exhibited moderate activities against the malarial parasite Plasmodium falciparum and Extracts of the sponge Pseudoceratina arabica proved to be very active against a series of Gram-positive and Gram-negative bacteria.
Ximaoglaucumins A - F, new cembranoids with anti-inflammatory activities from the South China Sea soft coral Sarcophyton glaucum.
- ChemistryBioorganic & medicinal chemistry
- 2021
Terpenoids from the Oleo-Gum-Resin of Boswellia serrata and Their Antiplasmodial Effects In Vitro.
- ChemistryPlanta medica
- 2017
In the course of our ongoing search for new natural products as leads against protozoal diseases, the dichloromethane extract of Indian frankincense, the oleo-gum-resin obtained from Boswellia…
Rare new bicyclic cembranoid ethers and a novel trihydroxy prenylated guaiane from the Xisha soft coral Lobophytum sp.
- ChemistryBioorganic chemistry
- 2020
Two new cembrane-type diterpenoids from the xisha soft coral Lemnalia flava.
- ChemistryFitoterapia
- 2019
Chemical Diversity and Biological Activity of Secondary Metabolites from Soft Coral Genus Sinularia since 2013
- Biology, ChemistryMarine drugs
- 2021
The structures, names, and pharmacological activities of compounds isolated from the genus Sinularia from 2013 to March 2021 are summarized in this review.
Erectsterates A and B, a pair of novel highly degraded steroid derivatives from the South China Sea soft coral Sinularia erecta
- ChemistrySteroids
- 2020
Structural diversity of bioactive steroid compounds isolated from soft corals in the period 2015–2020
- Biology, ChemistryThe Journal of Steroid Biochemistry and Molecular Biology
- 2022
Vulgarisins B–D, three novel diterpenoids with a rare skeleton isolated from Prunella vulgaris Linn
- Chemistry
- 2017
Rapid discovery and functional characterization of diterpene synthases from basidiomycete fungi by genome mining.
- Biology, EngineeringFungal genetics and biology : FG & B
- 2019
References
SHOWING 1-10 OF 159 REFERENCES
Anti-inflammatory cembranoids from the soft corals Sinularia querciformis and Sinularia granosa.
- ChemistryJournal of natural products
- 2008
Four new cembranoids, querciformolides A-D (1-4), along with two known cembraceoids, 7 and 8, have been isolated from the soft coral Sinulariaquerciformis and significantly inhibited the accumulation of the pro-inflammatory iNOS and COX-2 proteins in LPS-stimulated RAW264.7 macrophage cells.
Asteriscane-type sesquiterpenoids from the soft coral Sinularia capillosa.
- ChemistryJournal of natural products
- 2013
This is the first report of asteriscane-type sesquiterpenoids from soft corals, and capillosananes Q (17) and R (18) represent new seco-asteriscane skeletons.
Diterpenes from the Hainan soft coral Lobophytum cristatum Tixier-Durivault.
- ChemistryJournal of natural products
- 2011
The present work supports Faulkner's proposal of prenylgermacrene as the precursor of many diterpenes and the absolute configurations of lobophytumins A, B, and D-F were also tentatively suggested.
Studies of Australian Soft Corals. XXXX.1 The Natural Products Chemistry of Alcyonacean Soft Corals with Special Reference to the Genus Lobophytum
- Chemistry
- 2010
The eggs of the alcyonacean soft coral Lobophytum microlobulatum contain the known cembranoid diterpene 3,4-epoxynephthenol (9). This compound was not detected in the soft coral colony from which the…
Cembranoid Diterpenes Related to Sarcophytol A From the Soft Coral Sarcophyton trocheliophorum (Alcyonacea)
- Chemistry
- 1994
An investigation of metabolites from the soft coral Sarcophyton trocheliophorum collected at North East Reef, Orpheus Island, has yielded three simple cembranoid diterpenes , namely…
New cytotoxic cembrane based diterpenes from the soft corals Sarcophyton cherbonnieri and Nephthea sp.
- ChemistryOrganic & biomolecular chemistry
- 2003
The structures of the new compounds were elucidated by employing spectroscopic techniques (NMR, MS, UV, IR and CD) and were found to be cytotoxic towards several tumor cell lines.
Cembrane diterpenes from the southern African soft coral Cladiella kashmani.
- ChemistryJournal of natural products
- 2000
Two known cembrane diterpenes, flaccidoxide (1) and (1Z,3E,7E,11S, 12S,14S)-11,12-epoxy cembra-1,3,7-trien-14-ol (2), and the new cembrane diterpene flaccidoxide-13-acetate (3) were isolated from…
Several new isoprenoids from the soft coral sinularia erecta
- ChemistryJournal of natural products
- 1998
Eight compounds were isolated from the Indo-Pacific soft coral Sinularia erecta collected from the lagoon of Mayotte, Comoros Islands, northwest of Madagascar by means of 1D and 2D NMR and MS spectroscopy in addition to some chemical transformations.
Red Algae (Rhodophyta) from the Coast of Madagascar: Preliminary Bioactivity Studies and Isolation of Natural Products
- BiologyMarine drugs
- 2015
The crude extracts of Laurencia complanata exhibited antimicrobial activity against Bacillus cereus, Staphylococcus aureus, Streptococcus pneumoniae, and Candida albicans.
Cytotoxic Cembranes from Indonesian Specimens of the Soft Coral Nephthea sp
- ChemistryMarine drugs
- 2010
Methanol extracts of two specimens of the soft coral Nephthea sp. collected from the Seribu Islands, Indonesia, were active in an anticancer bioassay. One new (1) and four known diterpenes (2–5)…