Chemical coding of the hypothalamic neurones in metabolic control. I. Acetylcholine-sensitive neurones and glycogen synthesis in liver

@article{Matsushita1979ChemicalCO,
  title={Chemical coding of the hypothalamic neurones in metabolic control. I. Acetylcholine-sensitive neurones and glycogen synthesis in liver},
  author={Hiroshi Matsushita and Koichi Ishikawa and Takashi Shimazu},
  journal={Brain Research},
  year={1979},
  volume={163},
  pages={253-261}
}
To specify the lateral hypothalamic (LH) neurones concerned with regulation of liver glycogen metabolism, the changes in the activities of liver glycogen synthetase and phosphorylase were analyzed after microinjection of different neurotransmitters into the LH of rats. Cholinergic stimulation of the LH with minute amounts (5 x 10 -9 5 x 10 -s mole) of acetylcholine or carbachol resulted in a marked increase of the active form of glycogen synthetase, but it did not affect the phosphorylase… CONTINUE READING

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