Chemical and biological characterization of chicken insulin-like growth factor-II.

@article{Kallincos1990ChemicalAB,
  title={Chemical and biological characterization of chicken insulin-like growth factor-II.},
  author={Nick Kallincos and J. C. Wallace and Geoffrey Leonard Francis and F. John Ballard},
  journal={The Journal of endocrinology},
  year={1990},
  volume={124 1},
  pages={89-97}
}
Chicken insulin-like growth factor-II (cIGF-II) has been characterized by amino acid sequencing, by its receptor and binding protein interactions and by its biological activities in cultured cells in order to help define the significance of the peptide in the growth process. Chicken IGF-II has an N-terminal region and several amino acid substitutions in the mid-peptide region that differ from the mammalian growth factor. Nevertheless, cIGF-II was indistinguishable from ovine IGF-II in all assay… CONTINUE READING