Chemical and Biological Investigations of β‐Oligoarginines

@article{Seebach2004ChemicalAB,
  title={Chemical and Biological Investigations of $\beta$‐Oligoarginines},
  author={Dieter Seebach and Kenji Namoto and Yogesh R. Mahajan and Pascal Bindschaedler and Reiner Sustmann and Michael Kirsch and Neil S. Ryder and Markus Weiss and Markus Sauer and Christian Roth and Sabine Werner and Hans-Dietmar Beer and Christine Munding and Peter Walde and Matthias Richard Voser},
  journal={Chemistry \& Biodiversity},
  year={2004},
  volume={1}
}
In view of the important role arginine plays in living organisms as the free amino acid and, especially, as a residue in peptides and proteins, the homologous β‐homoarginines are central in our investigations of β‐peptides (Fig. 1). The preparation of β2‐homoarginine derivatives suitably protected for solution‐ or solid‐phase peptide syntheses is described with full experimental detail (9 and 12 in Scheme 1). The readily available Fmoc‐β3hArg(Boc)2‐OH is used for manual solid‐phase synthesis of… 

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