Chemical Profile and Anti-inflammatory Activity of Total Flavonoids from Glycyrrhiza Uralensis Fisch

@article{Yin2018ChemicalPA,
  title={Chemical Profile and Anti-inflammatory Activity of Total Flavonoids from Glycyrrhiza Uralensis Fisch},
  author={Lei Yin and Enshuang Guan and Yuanbin Zhang and Zhiheng Shu and Bing Wang and Xiuli Wu and Jing Chen and Jingxia Liu and Xueyan Fu and Weihong Sun and Meifeng Liu},
  journal={Iranian Journal of Pharmaceutical Research : IJPR},
  year={2018},
  volume={17},
  pages={726 - 734}
}
  • L. Yin, Enshuang Guan, +8 authors M. Liu
  • Published 1 April 2018
  • Chemistry, Medicine
  • Iranian Journal of Pharmaceutical Research : IJPR
Glycyrrhiza uralensis Fisch. (G. uralensis) is one of the most widely used herbal medicines. This study was designed to enrich total flavonoids (TFF) from G. uralensis. The chemical profile of TFF was identified by HPLC and colorimetric assay. The TFF mainly contained liquiritin apioside, liquiritin, isoliquiritin apioside, liquiritigenin and isoliquiritigenin without glycyrrhizic acid. To study the anti-inflammatory activity of TFF, the DMB-induced ear vasodilatation assay and carrageenan… Expand
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References

SHOWING 1-10 OF 39 REFERENCES
[Effects of glycyrrhizin acid and licorice flavonoids on LPS-induced cytokines expression in macrophage].
TLDR
The data presented here suggested that the glycyrrhizin acid and licorice flavonoids modulate various cytokines secreted by macrophages and were important anti-inflammatory constituent of Licorice. Expand
Anti-Inflammatory and Analgesic Activity of Total Flavone of Cunninghamia lanceolata
TLDR
It may be concluded that TFC showed both anti-inflammatory and analgesic effects, showing that it can be of importance in drug development, especially in the field of pain and inflammation. Expand
[Study on in vitro anti-inflammatory activity of total flavonoids from Glycyrrhizae Radix et Rhizoma and its ingredients].
TLDR
Activity-oriented extraction suggests that ethyl acetate fractions from Glycyrrhizae Radix et Rhizoma is one of components with anti-inflammatory activity. Expand
Anti-inflammatory and immunomodulatory activities of the extracts from the inflorescence of Chrysanthemum indicum Linné.
TLDR
Results reveal that CIBF possesses anti-inflammatory, humoral and cellular immunomodulatory and mononuclear phagocytic activities, probably due to the presence of flavonoids. Expand
Glycyrrhizin attenuates the development of carrageenan-induced lung injury in mice.
TLDR
It is reported here that glycyrrhizin (given at 10 mg/kg i.p. 5 min prior to carrageenan) exerts potent anti-inflammatory effects in this model of acute inflammation, and prevention of the activation of NF-kappaB and STAT-3 by glycy rhoizin reduces the development of acuteinflammatory. Expand
Experimental study on anti-inflammatory activity of a TCM recipe consisting of the supercritical fluid CO2 extract of Chrysanthemum indicum, Patchouli Oil and Zedoary Turmeric Oil in vivo.
TLDR
It is indicated that CPZ possessed a potent anti-inflammatory activity, which is indicated to be closely associated with its regulation on IL-1β and PGE(2) thereby mediating the inflammatory response acting at an appropriate level. Expand
Anti-inflammatory and analgesic activity of aqueous extract of Flos populi.
TLDR
The findings in this study suggest that the aqueous extract of Flos populi possesses anti-inflammatory and analgesic activities and may support the fact that this plant is used traditionally to cure inflammatory diseases. Expand
Glycyrrhizic Acid in the Treatment of Liver Diseases: Literature Review
TLDR
This review summarizes the current biological activities of GA and its medical applications in liver diseases and will open the door to novel agents in drug discovery and development from Chinese herbs. Expand
Anti-Inflammatory Activity of Licochalcone A Isolated from Glycyrrhiza inflata
TLDR
Licochalcone A showed remarkable effects against acute inflammation induced by xylene, and at the doses of 2.5, 5, 10 mg/kg (p.o.), licochalcone A reduced significantly paw edema induced by carrageenan compared to the control at the fourth hour. Expand
Glycyrrhizic acid and 18β-glycyrrhetinic acid modulate lipopolysaccharide-induced inflammatory response by suppression of NF-κB through PI3K p110δ and p110γ inhibitions.
TLDR
GA and 18βGA may provide an anti-inflammatory effect by attenuating the generation of excessive NO, PGE(2), and ROS and by suppressing the expression of pro-inflammatory genes through the inhibition of NF-κB and PI3K activity. Expand
...
1
2
3
4
...