Chemical Genetics Reveal the Novel Transmembrane Protein BIL4, Which Mediates Plant Cell Elongation in Brassinosteroid Signaling

@article{Yamagami2009ChemicalGR,
  title={Chemical Genetics Reveal the Novel Transmembrane Protein BIL4, Which Mediates Plant Cell Elongation in Brassinosteroid Signaling},
  author={Ayumi Yamagami and Miki Nakazawa and Minami Matsui and Masafumi Tujimoto and Masaaki Sakuta and Tadao Asami and Takeshi Nakano},
  journal={Bioscience, Biotechnology, and Biochemistry},
  year={2009},
  volume={73},
  pages={415 - 421}
}
Steroid hormones are conserved between animals and plants as signaling molecules to control growth and development. Plant steroid hormones, brassinosteroids (BRs), appear to play an important role in plant cell elongation. BRs bind to leucine-rich repeat kinase BRASSINOSTEROID-INSENSITIVE 1 (BRI1) localized to the plasma membrane, activate transcription factors in collaboration with cytosolic kinases and phosphatases, and regulate BR-responsive gene expression, but the details regarding the BR… 
Evolutionarily conserved BIL4 suppresses the degradation of brassinosteroid receptor BRI1 and regulates cell elongation
TLDR
It is demonstrated that BIL4 is expressed in early elongating cells and regulates cell elongation in Arabidopsis and also activates BR signaling and interacts with the BR receptor brassinosteroid insensitive 1 (BRI1) in endosomes.
Brassinosteroids regulate vacuolar morphology in root meristem cells of Arabidopsis thaliana
TLDR
The results suggest that BR signaling impacts vacuolar shape, and the effect of BIL4 and BR signaling on vacuole shape in root meristem cells using genetic and pharmacological approaches is suggested.
Brassinosteroid-related transcription factor BIL1/BZR1 increases plant resistance to insect feeding
TLDR
Over-Expression mutated bil1/bzr1 that is brassinosteroid master transcription factor gives resistance against the thrips feeding to plants, and resistance to thrip feeding caused by the BIL1/BZR1 gene may involve JA signaling.
YCZ-18 Is a New Brassinosteroid Biosynthesis Inhibitor
TLDR
Analysis of the mechanisms underlying the dwarf phenotype associated with YCZ-18 treatment of Arabidopsis indicated that the chemically induced dwarf phenotype was caused by a failure of cell elongation, and findings indicate that YCz-18 is a potentBR biosynthesis inhibitor and has a new target site, C23-hydroxylation in BR biosynthesis.
Fenarimol, a Pyrimidine-Type Fungicide, Inhibits Brassinosteroid Biosynthesis
TLDR
Fenarimol (FM), a pyrimidine-type fungicide, exhibits potent inhibitory activity against BR biosynthesis and induces dwarfism and the open cotyledon phenotype of Arabidopsis seedlings in the dark.
Chemical regulators of plant hormones and their applications in basic research and agriculture*
  • Kai Jiang, T. Asami
  • Environmental Science, Chemistry
    Bioscience, biotechnology, and biochemistry
  • 2018
TLDR
Chemical regulators that perturb plant hormone biosynthesis, metabolism, transport and signal transduction are expected to contribute to deciphering the complexity of the plant hormone network and to the development of specific PGRs.
Integrating Phosphoproteomics and Bioinformatics to Study Brassinosteroid-Regulated Phosphorylation Dynamics in Arabidopsis
TLDR
Through a large-scale dynamic profile of phosphoproteome coupled with bioinformatics, a complicated kinase-centered network related to BR-regulated growth was deciphered and suggested many downstream proteins of BR signaling are induced by phosphorylation via various kinases, not through transcriptional regulation.
Design and Synthesis of Function Regulators of Plant Hormones and their Application to Physiology and Genetics
TLDR
The design and synthesis of functional regulators of plant hormones (brassinosteroids, abscisic acid, strigolactones, and gibberellins) and their application to genetics are reported and both chemicals and genes are used for the improvement of crop and biomass production.
Ectopic expression of the atypical HLH FaPRE1 gene determines changes in cell size and morphology.
Golgi anti-apoptotic proteins are evolutionarily conserved ion channels that regulate cell death in plants
TLDR
It is proposed that AtGAAPs function as Golgi-localized ion channels that regulate cell death by affecting ionic homeostasis within the cell.
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