Diversity, utility, analytical methods and use implications of aroma-active compounds from select angiosperm families.
Given the wide ranging effects of EOs/ AAPs vis-a-vis the dearth of data on their levels in samples, it is recommended that their regulation in FPs should focus on controlling the wholesomeness of RMs; and on enforcing strict GMP in using such RMs.
Two new methoxylated flavones isolated from Casimiroa edulis La Llave and their MMP-9 inhibitory activity.
- ChemistryNatural product research
Casimiroa edulis La Llave is known to contain unusual 5,6-dimethoxyflavones bearing a variously oxygenated B-ring. Phytochemical investigation of the leaves and the roots of C. edulis achieved the…
Dictamnine delivered by PLGA nanocarriers ameliorated inflammation in an oxazolone-induced dermatitis mouse model.
- BiologyJournal of controlled release : official journal of the Controlled Release Society
LIPIDS, FATTY ACIDS AND PIGMENTS OF LEAVES DICTAMNUS CAUCASICUS FISCH. EX GROSSH. (RU-TACEAE)
Plants of the genus Dictamnus are a source of chemical compounds with different biological activity – alkaloids, bitterness, furocoumarins, saponins, essential oils. In the present work, the…
Phytochemistry, Pharmacology and Botanical Aspects of Hortia Species in the Search for Molecules with Bioactive Potential – A Review
An overview of the Hortia genus is given, focusing on morphological, phytochemical and biological activities to stimulate new studies about these species, which are used to treat fevers, malaria, diarrhea, vomiting and liver diseases.
Chemical composition and antimicrobial activity of the essential oil from the aerial part of Dictamnus dasycarpus Turcz.
- ChemistryIndustrial Crops and Products
Chemical constituents from the root bark of Dictamnus dasycarpus Turcz. (Rutaceae) and their chemotaxonomic significance
- Chemistry, BiologyBiochemical Systematics and Ecology
Dictamnine‐induced hepatotoxicity in mice: the role of metabolic activation of furan
- Biology, MedicineToxicology and applied pharmacology
Identification of In Vivo Metabolites of Dictamnine in Mice Using HPLC-LTQ-Orbitrap Mass Spectrometry
- Chemistry, BiologyJournal of analytical methods in chemistry
The major metabolic pathways of DIC in animal and human liver microsomes were confirmed in the present study, including o-demethylation, monohydroxylation, N-oxidation, and 2,3-olefinic epoxidation pathways.
SHOWING 1-10 OF 29 REFERENCES
Fraxinellone inhibits lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 expression by negatively regulating nuclear factor-kappa B in RAW 264.7 macrophages cells.
- BiologyBiological & pharmaceutical bulletin
The results suggest that the anti-inflammatory properties of fraxinellone are related to the down-regulations of iNOS and COX-2 due to NF-kappaB inhibition through the negative regulations of IKK and ERK1/2 phosphorylations in RAW 264.7 cells.
Selective triggering of apoptosis of concanavalin A-activated T cells by fraxinellone for the treatment of T-cell-dependent hepatitis in mice.
- Biology, MedicineBiochemical pharmacology
A novel trinorguaiane-type sesquiterpene from Dictamnus radicis
- ChemistryNatural product research
A novel trinorguaiane-type sesquiterpene named radicol was isolated from the petroleum ether–EtOAc–MeOH extracts of the root of Dictamnus radicis Cortex.
A system for screening agonists targeting β2-adrenoceptor from chinese medicinal herbs
- BiologyJournal of Zhejiang University SCIENCE B
A cell-based functional assay based on a common G protein-coupled receptor (GPCR) regulation mechanism and destabilized enhanced green fluorescent protein (d2EGFP) reporter gene technique was suitable for screening β2-adrenoceptor agonists.
Effects of a Dictamnus dasycarpus T. Extract on Allergic Models in Mice
- Medicine, BiologyBioscience, biotechnology, and biochemistry
DDT was effective in antagonizing certain pharmacological effects induced by compound 48/80 that occurred via both histamine and serotonin released from mast cells, and may be effective in the relief of symptoms of allergic atopic dermatitis and other allergy-related diseases.
Limonoids from the root of Dictamnus radicis cortex.
Chemical investigation of the roots of Dictamnus radicis Cortex led to the isolation of a new limonoid isodictamdiol (1) and a known dictamdiol (2), the first 5S/9S-type degraded limonoids, together…
Neuroprotective limonoids of root bark of Dictamnus dasycarpus.
- BiologyJournal of natural products
Compounds, 2, 3, 6, 9, 10, and 11 showed significant neuroprotective activity against glutamate-induced neurotoxicity in primary cultures of rat cortical cells at a concentration of 0.1 microM.
Composition, cytotoxicity and antimicrobial activity of essential oil from Dictamnus dasycarpus
- Biology, Medicine
Monoamine oxidase inhibitory coumarins from the aerial parts ofDictamnus albus
- Chemistry, BiologyArchives of pharmacal research
The methanol extract from the aerial parts of Dictamnus albus was active in inhibiting monoamine oxidase (MAO) from the mouse brain, and compounds1 and2 exhibited a competitive inhibition to MAO-B.
Solar simulator-induced phototoxicity of the furoquinoline alkaloid dictamnine compared to 8-methoxypsoralen and 5-methoxypsoralen.
- ChemistryPlanta medica
Dictamnine displayed concentration- and light-dependent phototoxic effects in both cell lines and may play a major role in the elicitation of phytophotodermatitis because of its abundance in plants of the Rutaceae family.