Chemical Constituents and Biological Activity Profiles on Pleione (Orchidaceae)

@article{Wu2019ChemicalCA,
  title={Chemical Constituents and Biological Activity Profiles on Pleione (Orchidaceae)},
  author={Xiaoqian Wu and Wei Li and Jingxin Chen and Junwen Zhai and Hui-you Xu and Lin Ni and Sha-sha Wu},
  journal={Molecules},
  year={2019},
  volume={24}
}
Pleione (Orchidaceae) is not only famous for the ornamental value in Europe because of its special color, but also endemic in Southern Asia for its use in traditional medicine. A great deal of research about its secondary metabolites and biological activities has been done on only three of 30 species of Pleione. Up to now, 183 chemical compounds, such as phenanthrenes, bibenzyls, glucosyloxybenzyl succinate derivatives, flavonoids, lignans, terpenoids, etc., have been obtained from Pleione… 
Chemical Constituents of Species in the Genus Pleione (Orchidaceae) and the Implications from Molecular Phylogeny
TLDR
High performance liquid chromatography fingerprint of Pleione plants was established and it is suggested that species with a large pseudobulb and with high content of a certain compound should be given priority in future artificial cultivation and medicinal cultivar breeding.
Two new bibenzyls from Pleione grandiflora (Rolfe) Rolfe and their antioxidant activity.
Two new bibenzyls (1 and 2) were isolated from the pseudobulbs of Pleione grandiflora (Rolfe) Rolfe along with six known compounds, including isoarundinin I (3), isoarundinin II (4), bulbocodin D
Lignans and Their Derivatives from Plants as Antivirals
TLDR
Two types of antiviral lignan—podophyllotoxin and bicyclol, which are used to treat venereal warts and chronic hepatitis B in clinical, serve as examples of using lignans for antivirals—are discussed in some detail.
A Walk Through the Maze of Secondary Metabolism in Orchids: A Transcriptomic Approach
TLDR
Comparing analysis of high-throughput transcript data involving gene identification, functional annotation, and differential expression in more than 30 orchid transcriptome data sets helps elucidate the role of various factors in alkaloid and flavonoid biosynthesis and provide specific insights to the potential gene targets for drug discovery.
Xylochemical Synthesis and Biological Evaluation of Shancigusin C and Bletistrin G ‡
TLDR
The cytotoxic properties of shancigusin C (1) and bletistrin G (2) against tumor cells suggest suitability as a starting point for further structural variation.
A New Phenanthrene Derivative with α-Glucosidase Inhibitory Activity from Pleione maculata
A new phenanthrene, 2,3,7-trihydroxy-4,8-dimethoxyphenanthrene ( 1 ), was isolated from Pleione maculata . Its structure was determined on the basis of NMR (1D and 2D) and HR-ESI-MS data. The new
Biomass and Active Compounds Accumulation of the Medicinal Orchid Pleione bulbocodioides in Response to Light Intensity and Irrigation Frequency
Pseudobulbs of Pleione species are widely used as traditional medicine in Asian countries, but the mechanism of active compound accumulation remains unclear. In the present study, we investigated the
Orchids and their mycorrhizal fungi: an insufficiently explored relationship
TLDR
A putative model representing the different molecular strategies that OM fungi might employ to establish this association with arbuscular mycorrhiza is proposed and targeted and untargeted metabolomics studies with special attention to each partner’s contribution are encouraged and some technical approaches are proposed.
Identification and Characterization of Two Bibenzyl Glycosyltransferases from the Liverwort Marchantia polymorpha
TLDR
Two bibenzyl UDP-glucosyltransferases named MpUGT737B1 and MpugT741A1 from the model liverwort Marchantia polymorpha are identified and should provide candidate genes for the synthesis of bioactive bibensyl O-glUCosides and the improvement of plant antioxidant capacity.
...
...

References

SHOWING 1-10 OF 69 REFERENCES
Studies on Chemical Constituents of the Tubers of Gymnadenia conopsea
OBJECTIVE To study chemical constituents of the tubers of Gymnadenia conopsea.METHODS The compounds were isolated by column chromatographic methods,their structures were elucidated on the basis of
[Chemical constituents from Pleione bulbocodioides].
TLDR
Nine compounds were isolated from the EtOAc extract in the rhizoma of Pleione bulbocodioides, and compounds I - IX are isolated from this plant for the first time.
Cytotoxic phenolics from Bulbophyllum odoratissimum
[Chemical constituents from Pleione yunnanensis].
TLDR
The chemical constituents from pseudobulbs of Pleione yunnanensis, one of the source of traditional Chinese medicine "Shancigu", were investigated by various chromatography methods, including silica gel, ODS, Sephadex LH-20, and semi-preparative HPLC.
Phenanthrenequinone enantiomers with cytotoxic activities from the tubers of Pleione bulbocodioides.
TLDR
Eight new phenanthrenequinones (four pairs of enantiomers), named bulbocodioidins A-D (1-4), have been isolated from the ethanolic extract of tubers of Pleione bulbocidioides by extensive NMR analysis combined with experimental and calculated ECD data analyses.
New Polyphenols and Triterpene from the Pseudobulbs of Pleione Formosana
Three new polyphenolic compounds including a dihydrophenanthrene, pleioanthrenin (1), two bibenzyls, pleiobibenzynin A (2) and B (3), and a new cycloartane triterpenoid, (24R)-cyclomargenyl
Shancigusins E‐I, five new glucosides from the tubers of Pleione yunnanensis
TLDR
Five new glucosides, shancigusins E‐I (1–5) were isolated from the tubers of Pleione yunnanensis (Rolfe) together with 18 known compounds, determined by extensive analyses of their spectroscopic data.
Lignans and a bichroman from Pleione bulbocodioides
...
...