Chemical Approaches to DNA Nanotechnology

  title={Chemical Approaches to DNA Nanotechnology},
  author={Masayuki Endo and Hiroshi Sugiyama},
Due to its self‐assembling nature, DNA is undoubtedly an excellent molecule for the creation of various multidimensional nanostructures and the placement of functional molecules and materials. DNA molecules behave according to the programs of their sequences. Mixtures of numbers of DNA molecules can be placed precisely and organized into single structures to form nanoarchitectures. Once the appropriate sequences for the target nanostructure are established, the predesigned structure can be… 

Structural DNA Nanotechnology: From Design to Applications

The principles and some examples of applications of both the tile-based and DNA origami methods are discussed, and the origami method would appear to be more appropriate for the construction of bigger, more sophisticated and exactly defined structures.

Direct Nanofabrication Using DNA Nanostructure.

This chapter focuses on the proof-of-principle study to directly convert the structural information of DNA nanostructure to various kinds of materials by nanofabrication.

DNA Origami-based Construction of Meso-scale Multi-dimensional Architects and Expression of the Functionality in the Designed DNA Nanospace

This review focuses on and describes the following DNA origami-templated molecular assembly, programmed DNA Origami assembly, design and construction of various three-dimensionalDNA origami structures, and single molecular observation on designed DNA origAMI.

Introduction: Overview of DNA Origami as Biomaterials and Application

This chapter mainly introduced the basics of DNA origami technique, the development of art-like programmed nanostructures and the progress of applications in biological systems, and summarized some representative progresses of DNA Origami method in various field.

Molecular architectonics of DNA for functional nanoarchitectures

The advantages and ability of functional DNA nanoarchitectonics to overcome the trivial drawbacks of classical DNA nanotechnology to fulfill realistic and practical applications are highlighted, and an outlook on future developments is presented.

DNA nanostructure based nanofabrication

  • F. Zhou
  • Biology, Materials Science
  • 2016
This dissertation focuses on the proof-of-principle study to convert the structural information of DNA nanostructure to various kinds of material, and identifies conditions for high contrast, high resolution, and high resolution pattern transfer to SiO2 fromDNA nanostructures as well as individual double stranded DNA.

DNA architectures for templated material growth

A methodology that allows for the coupling of biology and electronic materials is presented, where double stranded DNA serves as a template for electronic material growth. Self-assembled DNA

Metal-complex/DNA conjugates: a versatile building block for DNA nanoarrays.

The use of DNA networks as templates for forming nanoarrays of metallic centres shows an exciting potential to generate addressable nanostructures in emerging technologies, such as nanotechnology, biosensing or biocomputing.

Nature-Inspired Design of Smart Biomaterials Using the Chemical Biology of Nucleic Acids

The design of nature-inspired smart biomaterials that are based on the chemical biology of nucleic acids are detailed, which allow the real-time visualization of the complicated single-molecule interactions.

DNA architectonics: towards the next generation of bio-inspired materials.

The use of DNA in nanobiotechnology has advanced to a stage at which almost any two or three dimensional architecture can be designed with high precision, and the inclusion of designer nucleoside analogues adds functionality with addressable groups, which have an influence on the function of the DNA nano-objects.



Assembling Materials with DNA as the Guide

DNA's remarkable molecular recognition properties and structural features make it one of the most promising templates to pattern materials with nanoscale precision, and it can be used to precisely position proteins, nanoparticles, transition metals, and other functional components into deliberately designed patterns.

Addressing single molecules on DNA nanostructures.

These methods provide a versatile and programmable way to control the structure and architecture of DNA nanostructures and create well-defined DNA architectures of increasing complexity.

A modular approach to DNA-programmed self-assembly of macromolecular nanostructures.

Direct DNA-programmed multicomponent coupling of custom designed organic modules is described and the macromolecular structures obtained are highly conjugated potentially conducting nanoscaffolds.

Programmable self-assembly of metal ions inside artificial DNA duplexes

The DNA structure is used as a matrix to program robustly the complexation of different metal ions under precise control with regard to element, number and composition.

DNA-templated self-assembly of two-dimensional and periodical gold nanoparticle arrays.

When NPs are assembled onto self-assembled DNA lattices, the periodicities and interparticle spacings defined by the DNA scaffolds can be readily adjusted, with nanometer spatial precisions, which provides exquisite control in the construction of rationally defined NP architectures.

DNA-templated self-assembly of protein and nanoparticle linear arrays.

An experiment using a linear array of DNA triple crossover tiles to controllably template the self-assembly of single-layer or double-layer linear arrays of streptavidin molecules and streptavin-conjugated nanogold particles through biotin-streptavid in interaction is reported.

Programmed Materials Synthesis with DNA.

The purpose of this review is to summarize advances made involving new strategies that rely on the use of both naturally occurring DNA and synthetic oligonucleotides to assemble nanoscale nonbiological building blocks into extended mesoand macroscopic structures.

Self-assembly of a nanoscale DNA box with a controllable lid

The DNA origami method is extended into three dimensions by creating an addressable DNA box that can be opened in the presence of externally supplied DNA ‘keys’, and controlled access to the interior compartment of this DNA nanocontainer could yield several interesting applications.

Control of Self-Assembly of DNA Tubules Through Integration of Gold Nanoparticles

Electron tomography revealed a left-handed chirality in the spiral tubes, double-wall tube features, and conformational transitions between tubes.

Controlled nucleation of DNA metallization.

Novel procedures aimed at increasing the selectivity of the metallization process are the decoration of DNA with functional groups to control the spatial distribution of the nucleation sites, the photochemical deposition of silver on DNA strands, and the formation of DNA–Pt adducts as precursors for metal deposition on DNA.