Chemerin--a new adipokine that modulates adipogenesis via its own receptor.

  title={Chemerin--a new adipokine that modulates adipogenesis via its own receptor.},
  author={Sang-gun Roh and Shenglei Song and Ki-choon Choi and Kazuo Katoh and Val{\'e}rie Wittamer and Marc Parmentier and Shin-ichi Sasaki},
  journal={Biochemical and biophysical research communications},
  volume={362 4},
Chemerin, an 18 kDa protein secreted by adipose tissue, was reported to modulate immune system function through its binding to the chemerin receptor (chemerinR). We herein demonstrate that chemerin also influences adipose cell function. Our data showed that chemerin and chemerinR mRNA expressions were highly expressed in adipose tissues, and that their expression levels were up-regulated in mice fed a high-fat diet. Both chemerin and chemerinR mRNA expression dramatically increased during the… CONTINUE READING
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