Chelidonium majus L. does not potentiate the hepatic effect of acetaminophen.

@article{Mazzanti2013ChelidoniumML,
  title={Chelidonium majus L. does not potentiate the hepatic effect of acetaminophen.},
  author={G. Mazzanti and A. Di Sotto and S. Di Giacomo and Federico Durazzi and P. Mariani and M. Nicoletti and C. Mammola and A. Vitalone},
  journal={Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie},
  year={2013},
  volume={65 7-8},
  pages={
          1117-20
        }
}
  • G. Mazzanti, A. Di Sotto, +5 authors A. Vitalone
  • Published 2013
  • Medicine
  • Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie
AIM The present study assessed the ability of Chelidonium majus to potentiate the hepatic effect of a sub-toxic dose of acetaminophen, in rats. RESULTS C. majus, when administered alone, did not alter the liver function parameters in male, whereas an increase in fibrinogen level was found in female rats. Moreover, it did not affect the hepatic histomorphology in both male and female rats. The sub-toxic dose of acetaminophen induced: a significant increase in activated partial thromboplastin… Expand
Hepatotoxicity induced by greater celandine (Chelidonium majus L.): a review of the literature.
One new alkaloid from Chelidonium majus L.

References

SHOWING 1-10 OF 21 REFERENCES
Chelidonium majus is not hepatotoxic in Wistar rats, in a 4 weeks feeding experiment.
Potentiation of paracetamol and carbon tetrachloride-induced hepatotoxicity in rodents by the food additive vanillin.
  • K. Janbaz, A. Gilani
  • Chemistry, Medicine
  • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 1999
Hepatitis from Greater celandine (Chelidonium majus L.): review of literature and report of a new case.
Herbal hepatotoxicity by Greater Celandine (Chelidonium majus): causality assessment of 22 spontaneous reports.
Suspected Greater Celandine hepatotoxicity: liver-specific causality evaluation of published case reports from Europe
Parallelogram approach using rat-human in vitro and rat in vivo toxicogenomics predicts acetaminophen-induced hepatotoxicity in humans.
Drug‐induced hepatic injury
  • G. Farrell
  • Medicine
  • Journal of gastroenterology and hepatology
  • 1997
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