Checks and Balances in Autoimmune Vasculitis

@inproceedings{Cadena2018ChecksAB,
  title={Checks and Balances in Autoimmune Vasculitis},
  author={Rebeca Hid Cadena and Wayel Habib Abdulahad and Geke A. P. Hospers and Troels Wind and Annemieke M. H. Boots and Peter Heeringa and Elisabeth Brouwer},
  booktitle={Front. Immunol.},
  year={2018}
}
Age-associated changes in the immune system including alterations in surface protein expression are thought to contribute to an increased susceptibility for autoimmune diseases. The balance between the expression of coinhibitory and costimulatory surface protein molecules, also known as immune checkpoint molecules, is crucial in fine-tuning the immune response and preventing autoimmunity. The activation of specific inhibitory signaling pathways allows cancer cells to evade recognition and… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 109 REFERENCES

Immunoinhibitory checkpoint deficiency in medium and large vessel vasculitis.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2017
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination

  • Nature Reviews Clinical Oncology
  • 2016
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Bevacizumab plus ipilimumab in patients with metastatic melanoma.

  • Cancer immunology research
  • 2014
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Pathogenesis of ANCA-associated vasculitis: new possibilities for intervention.

  • American journal of kidney diseases : the official journal of the National Kidney Foundation
  • 2013
VIEW 8 EXCERPTS
HIGHLY INFLUENTIAL

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