Checkpoint Blockade Rescues the Repressive Effect of Histone Deacetylases Inhibitors on γδ T Cell Function

@inproceedings{Bhat2018CheckpointBR,
  title={Checkpoint Blockade Rescues the Repressive Effect of Histone Deacetylases Inhibitors on γδ T Cell Function},
  author={Sajad Ahmad Bhat and Disha Mohan Vedpathak and Shubhada Vivek Chiplunkar},
  booktitle={Front. Immunol.},
  year={2018}
}
Histone deacetylases (HDAC) are one of the key epigenetic modifiers that control chromatin accessibility and gene expression. Their role in tumorigenesis is well established and HDAC inhibitors have emerged as an effective treatment modality. HDAC inhibitors have been investigated for their specific antitumor activities and also clinically evaluated in… CONTINUE READING