Check and mate to exosomal extracellular miRNA: new lesson from a new approach

@inproceedings{Turchinovich2015CheckAM,
  title={Check and mate to exosomal extracellular miRNA: new lesson from a new approach},
  author={Andrey A Turchinovich and Alexander G. Tonevitsky and William Chi-shing Cho and Barbara Burwinkel},
  booktitle={Front. Mol. Biosci.},
  year={2015}
}
MicroRNAs (miRNAs) are 19-24 nt single-stranded RNAs which regulate gene expression by sequence-specific targeting of corresponding mRNAs. Extracellular miRNAs have been consistently detected in all human body fluids, and were shown to be prominent non-invasive biomarkers for various diseases including cancer. Albeit biological function of cell-free miRNA remains questionable, some studies demonstrated that exosomes encapsulated extracellular miRNAs could mediate inter-cellular signaling. While… CONTINUE READING

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