Chaunopycnis pustulata sp. nov., a new clavicipitalean anamorph producing metabolites that modulate potassium ion channels

  title={Chaunopycnis pustulata sp. nov., a new clavicipitalean anamorph producing metabolites that modulate potassium ion channels},
  author={Gerald F. Bills and Jon D. Polishook and Michael A. Goetz and Raymond F. Sullivan and James F. White},
  journal={Mycological Progress},
Two morphologically similar strains of hyphomycetous fungi, MF5785 and MF5638, produced potent indole diterpene antagonists of the calcium-gated potassium ion channel, Maxi-K, and a diterpene blocker (nalanthalide) of the voltage-gated potassium channel, Kv 1.3, respectively. The two strains were tentatively identified in the literature as Nalanthamala species. Analyses of their secondary metabolite profiles by HPLC and mass spectroscopy demonstrated that both produced a series of indole… 

Tolypoalbin, a new tetramic acid from Tolypocladium album TAMA 479

In the course of the investigation on metabolite diversity in hypocrealean fungi, a Tolypocladium strain was found to produce a new tetramic acid derivative (tolypoalbin, 1) and its known congener (F-14329, 2).

Comprehensive Review of Tolypocladium and Description of a Novel Lineage from Southwest China

Phylogenetic analyses based on SSU, LSU, ITS, TEF1-α and RPB2 sequence data showed T. inusitaticapitatum to be an independent lineage separated from T. flavonigrum in the clade comprising T. capitatum, T. fractum and T. longisegmentatum.

Tolypocladium reniformisporum sp. nov. and Tolypocladium cylindrosporum (Ophiocordycipitaceae, Hypocreales) co-occurring on Ophiocordyceps sinensis

Two Tolypocladium species, Tolypocladium reniformisporum sp. nov., and T. cylindrosporum , were isolated from the sclerotium of a naturally occurring Ophiocordyceps sinensis specimen in the Baima

Phylogenetic-based nomenclatural proposals for Ophiocordycipitaceae (Hypocreales) with new combinations in Tolypocladium

This work proposes to protect and to suppress names within Ophiocordycipitaceae, and to present taxonomic revisions in the genus Tolypocladium, based on rigorous and extensively sampled molecular phylogenetic analyses.

Phylogeny and Systematics of the Genus Tolypocladium (Ophiocordycipitaceae, Hypocreales)

The results indicated that species of Tolypocladium were best delimited by rpb1 sequence data, followed by the sequence data for the rpb2, tef-1α, and ITS provided regions.

Hypomiltin, a novel azaphilone from Hypoxylon hypomiltum, and chemotypes in Hypoxylon sect. Hypoxylon as inferred from analytical HPLC profiling

Characteristic secondary metabolite profiles of several further Hypoxylon species are correlated with the colours of their taxonomically significant KOH-extractable pigments, based on analytical HPLC data.

Classification of the guava wilt fungus Myxosporium psidii, the palm pathogen Gliocladium vermoesenii and the persimmon wilt fungus Acremonium diospyri in Nalanthamala.

Nalanthamala, therefore, is the appropriate anamorph genus for Myxosporium psidii, while MyxOSporium is a nomen nudum (based on M. croceum).

A New Report on Three Species of Sordariomycetes Class Isolated from Soil in Korea

Three fungal strains belonging to the class Sordariomycetes, namely BH-06, 17-039 and BE12-1, were isolated from soils in Korea and identified as Chaunopycnis alba, Myrothecium cinctum and Humicola



Molecular studies of the Bionectriaceae using large subunit rDNA sequences

Although classified in the Bionectriaceae based on morphological evidence, species of the tropical genus Peethambara and their Didymostilbe anamorphs and the morphologically similar anamorph genera, Albosynnema and Myrothecium, fall outside of any of the supported clades.

Phylogeny of caddisflies (Insecta, Trichoptera)

Equally and differentially weighted parsimony analyses were conducted in order to present a phylogeny of Trichoptera, including 43 of 45 families, which closely resembles that proposed by Herbert Ross with respect to the relationships among suborders, with a monophyletic Annulipalpia at the base of the tree, and a clade consisting of Spicipalpia plus a monopyletic IntegripalPia.

Intraspecific diversity in the fungal speciesChaunopycnis alba: Implications for microbial screening programs

Analysis of intraspecific variation among 84 isolates of the anamorphic fungus Chaunopycnis alba showed high genetic, metabolic and physiological diversity within this species, and the suggestion that for pharmaceutical screening programs samples should be collected from a diversity of different geographical and climatic locations.

Nodulisporic Acid A, a Novel and Potent Insecticide from a Nodulisporium Sp. Isolation, Structure Determination, and Chemical Transformations

The potent insecticidal agent nodulisporic acid A (1a), representative of a new class of indole terpenes, was isolated from fermentations of a Nodulisporium sp. Nodulisporic acid A was active against

Terpendoles, novel ACAT inhibitors produced by Albophoma yamanashiensis. I. Production, isolation and biological properties.

Evaluation of terpendoles from the culture broth of a fungal strain FO-2546 indicated that terpendole D exhibited the highest specificity (cytotoxicity vs. ACAT inhibition) among microbial ACAT inhibitors the authors discovered so far.

Features and phylogenetic status of an enigmatic clavicipitalean fungus Neoclaviceps monostipa gen. et sp. nov.

Phylogenetic analysis of the 26S large subunit rDNA suggests that Neoclaviceps along with genus Myriogenospora are evolutionary intermediate between Claviceps and Balansia.

Phylogenetic relationships in the mushroom genus Coprinus and dark-spored allies based on sequence data from the nuclear gene coding for the large ribosomal subunit RNA: divergent domains, outgroups, and monophyly.

Phylogenetic analyses employing topological constraints suggest that none of the major taxonomic systems proposed for subgeneric classification is able to completely reflect phylogenetic relationships in Coprinus.

Entomopathogenic species of the hyphomycete genus Tolypocladium