Chaunopycnis pustulata sp. nov., a new clavicipitalean anamorph producing metabolites that modulate potassium ion channels

@article{Bills2006ChaunopycnisPS,
  title={Chaunopycnis pustulata sp. nov., a new clavicipitalean anamorph producing metabolites that modulate potassium ion channels},
  author={Gerald F Bills and Jon D. Polishook and Michael A. Goetz and Raymond F. Sullivan and James F White},
  journal={Mycological Progress},
  year={2006},
  volume={1},
  pages={3-17}
}
Two morphologically similar strains of hyphomycetous fungi, MF5785 and MF5638, produced potent indole diterpene antagonists of the calcium-gated potassium ion channel, Maxi-K, and a diterpene blocker (nalanthalide) of the voltage-gated potassium channel, Kv 1.3, respectively. The two strains were tentatively identified in the literature as Nalanthamala species. Analyses of their secondary metabolite profiles by HPLC and mass spectroscopy demonstrated that both produced a series of indole… Expand

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