Chasing 100%: the use of hypertonic saline to improve early, primary fascial closure after damage control laparotomy.

@article{Harvin2013Chasing1T,
  title={Chasing 100%: the use of hypertonic saline to improve early, primary fascial closure after damage control laparotomy.},
  author={John A Harvin and Mark M Mims and Juan Carlos Duchesne and Charles S. Cox and Charles E. Wade and John B. Holcomb and Bryan A. Cotton},
  journal={The journal of trauma and acute care surgery},
  year={2013},
  volume={74 2},
  pages={426-30; discussion 431-2}
}
BACKGROUND Failure to achieve fascial closure after damage control laparotomy (DCL) is associated with increased morbidity and long-term disability. In addition, early closure is associated with reduces infectious, wound, and pulmonary complications. We hypothesized that hypertonic saline (HTS), which attenuates resuscitation-induced intestinal edema in animals, would improve early primary fascial closure (EPFC) rates. METHODS This is a retrospective study of trauma patients undergoing DCL… CONTINUE READING
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