Chasing 100%: the use of hypertonic saline to improve early, primary fascial closure after damage control laparotomy.

  title={Chasing 100%: the use of hypertonic saline to improve early, primary fascial closure after damage control laparotomy.},
  author={John A Harvin and Mark M Mims and Juan Carlos Duchesne and Charles S. Cox and Charles E. Wade and John B. Holcomb and Bryan A. Cotton},
  journal={The journal of trauma and acute care surgery},
  volume={74 2},
  pages={426-30; discussion 431-2}
BACKGROUND Failure to achieve fascial closure after damage control laparotomy (DCL) is associated with increased morbidity and long-term disability. In addition, early closure is associated with reduces infectious, wound, and pulmonary complications. We hypothesized that hypertonic saline (HTS), which attenuates resuscitation-induced intestinal edema in animals, would improve early primary fascial closure (EPFC) rates. METHODS This is a retrospective study of trauma patients undergoing DCL… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 7 times. VIEW TWEETS


Publications citing this paper.
Showing 1-9 of 9 extracted citations

The open abdomen in trauma and non-trauma patients: WSES guidelines

World journal of emergency surgery : WJES • 2018
View 8 Excerpts
Highly Influenced

Fluid Resuscitation for Hemorrhagic Shock in Tactical Combat Casualty Care: TCCC Guidelines Change 14-01--2 June 2014.

Journal of special operations medicine : a peer reviewed journal for SOF medical professionals • 2014


Publications referenced by this paper.
Showing 1-10 of 33 references

Purposeful selection of variables in logistic regression

Source Code for Biology and Medicine • 2008
View 4 Excerpts
Highly Influenced

CC.One hundred percent fascial approximation can be achieved in the postinjuryopen abdomenwith a sequential closure protocol

BurlewCC, EE Moore, +3 authors Barnett
J Trauma • 2012

patients with hypertonic saline V without dextran V inhibits neutrophil and endothelial cell activation

EM Bulger, J Cuschieri, K Warner, RV Maier

Loss of protein, immunoglobulins, and electrolytes in exudates from negative pressure wound therapy.

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition • 2010
View 1 Excerpt

Similar Papers

Loading similar papers…