Charged multivesicular body protein 2B (CHMP2B) of the endosomal sorting complex required for transport-III (ESCRT-III) polymerizes into helical structures deforming the plasma membrane.

Abstract

The endosomal sorting complexes required for transport (ESCRT-0-III) allow membrane budding and fission away from the cytosol. This machinery is used during multivesicular endosome biogenesis, cytokinesis, and budding of some enveloped viruses. Membrane fission is catalyzed by ESCRT-III complexes made of polymers of charged multivesicular body proteins… (More)
DOI: 10.1074/jbc.M111.283671

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Cite this paper

@article{Bodon2011ChargedMB, title={Charged multivesicular body protein 2B (CHMP2B) of the endosomal sorting complex required for transport-III (ESCRT-III) polymerizes into helical structures deforming the plasma membrane.}, author={Gilles Bodon and Romain Chassefeyre and Karin Pernet-Gallay and Nicolas G Martinelli and Gr{\'e}gory Effantin and David Lutje Hulsik and Agn{\`e}s Belly and Yves Goldberg and Christine Chatellard-Causse and B{\'e}atrice Blot and Guy Schoehn and Winfried Weissenhorn and R{\'e}my Sadoul}, journal={The Journal of biological chemistry}, year={2011}, volume={286 46}, pages={40276-86} }