Charge movement and calcium currents in skeletal muscle fibers are enhanced by GTPγS

@article{Garcia2004ChargeMA,
  title={Charge movement and calcium currents in skeletal muscle fibers are enhanced by GTPγS},
  author={Jonathan Garcia and R. Gamboa-Aldeco and Enrico Stefani},
  journal={Pfl{\"u}gers Archiv},
  year={2004},
  volume={417},
  pages={114-116}
}
G-proteins play several regulatory roles in the cell. They can modulate ionic channels directly or in association with second messengers. In skeletal muscle, G-proteins modulate the activity of calcium channels either by acting directly on the channel and/or through a cAMP-dependent phosphorylating mechanism19. The activation of G-proteins by GTPγS can also… CONTINUE READING