Charge-associated effects of fullerene derivatives on microbial structural integrity and central metabolism.

@article{Tang2007ChargeassociatedEO,
  title={Charge-associated effects of fullerene derivatives on microbial structural integrity and central metabolism.},
  author={Yinjie J. Tang and Jared M Ashcroft and Ding Chen and Guangwei Min and Chul-hyun Kim and Bipasha Murkhejee and Carolyn Larabell and Jay D Keasling and F. Frank Chen},
  journal={Nano letters},
  year={2007},
  volume={7 3},
  pages={754-60}
}
The effects of four types of fullerene compounds (C60, C60-OH, C60-COOH, C60-NH2) were examined on two model microorganisms (Escherichia coli W3110 and Shewanella oneidensis MR-1). Positively charged C60-NH2 at concentrations as low as 10 mg/L inhibited growth and reduced substrate uptake for both microorganisms. Scanning electron microscopy (SEM) revealed damage to cellular structures. Neutrally charged C60 and C60-OH had mild negative effects on S. oneidensis MR-1, whereas the negatively… CONTINUE READING
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