Characterizing the subjective, psychomotor, and physiological effects of a hydrocodone combination product (Hycodan) in non-drug-abusing volunteers

@article{Zacny2002CharacterizingTS,
  title={Characterizing the subjective, psychomotor, and physiological effects of a hydrocodone combination product (Hycodan) in non-drug-abusing volunteers},
  author={James P. Zacny},
  journal={Psychopharmacology},
  year={2002},
  volume={165},
  pages={146-156}
}
  • J. Zacny
  • Published 2002
  • Medicine
  • Psychopharmacology
Abstract Rationale. The subjective, psychomotor, and physiological effects of prescription compounds containing the opioid hydrocodone have not been studied in a population of non-drug-abusing people who might be prescribed these compounds for cough or pain relief. Objectives. To characterize the effects of a hydrocodone combination product, Hycodan, which contains hydrocodone and a peripherally-acting anticholinergic, homatropine, in non-drug-abusing volunteers. Methods. Eighteen volunteers… 
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Although oxycodone produced abuse liability-related subjective effects, it also produced unpleasant effects, a phenomenon the authors have observed in other opioid studies in non-drug-abusing volunteers.
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The opioid rotation ratio of hydrocodone to strong opioids in cancer patients.
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