Characterizing the bending and flexibility induced by bulges in DNA duplexes.

@article{Schreck2015CharacterizingTB,
  title={Characterizing the bending and flexibility induced by bulges in DNA duplexes.},
  author={John S. Schreck and Thomas E. Ouldridge and Flavio Romano and Ard A. Louis and Jonathan P. K. Doye},
  journal={The Journal of chemical physics},
  year={2015},
  volume={142 16},
  pages={
          165101
        }
}
Advances in DNA nanotechnology have stimulated the search for simple motifs that can be used to control the properties of DNA nanostructures. One such motif, which has been used extensively in structures such as polyhedral cages, two-dimensional arrays, and ribbons, is a bulged duplex, that is, two helical segments that connect at a bulge loop. We use a coarse-grained model of DNA to characterize such bulged duplexes. We find that this motif can adopt structures belonging to two main classes… 
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