Characterizing single suspended cells by optorheology.

  title={Characterizing single suspended cells by optorheology.},
  author={Falk Wottawah and Stefan Schinkinger and Bryan Lincoln and Susanne Ebert and Karla A Mueller and F. Sauer and Kort A Travis and J. Guck},
  journal={Acta biomaterialia},
  volume={1 3},
The measurement of the mechanical properties of individual cells has received much attention in recent years. In this paper we describe the application of optically induced forces with an optical stretcher to perform step-stress experiments on individual suspended fibroblasts. The conversion from creep-compliance to frequency-dependent complex shear modulus reveals characteristic viscoelastic signatures of the underlying cytoskeleton and its dynamic molecular properties. Both normal and… CONTINUE READING

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