Characterizing extravascular fluid transport of macromolecules in the tumor interstitium by magnetic resonance imaging.

@article{Pathak2005CharacterizingEF,
  title={Characterizing extravascular fluid transport of macromolecules in the tumor interstitium by magnetic resonance imaging.},
  author={Arvind P. Pathak and Dmitri Artemov and B. Douglas Ward and David M. Jackson and Michal Neeman and Zaver M. Bhujwalla},
  journal={Cancer research},
  year={2005},
  volume={65 4},
  pages={1425-32}
}
Noninvasive imaging techniques to image and characterize delivery and transport of macromolecules through the extracellular matrix (ECM) and supporting stroma of a tumor are necessary to develop treatments that alter the porosity and integrity of the ECM for improved delivery of therapeutic agents and to understand factors which influence and control delivery, movement, and clearance of macromolecules. In this study, a noninvasive imaging technique was developed to characterize the delivery as… CONTINUE READING

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