Characterizing acetogenic metabolism using a genome-scale metabolic reconstruction of Clostridium ljungdahlii

@inproceedings{Nagarajan2013CharacterizingAM,
  title={Characterizing acetogenic metabolism using a genome-scale metabolic reconstruction of Clostridium ljungdahlii},
  author={Harish Nagarajan and Merve Şahin and Juan Nogales and Haythem Latif and Derek R. Lovley and A Alrashed Ebrahim and Karsten Zengler},
  booktitle={Microbial cell factories},
  year={2013}
}
BACKGROUND The metabolic capabilities of acetogens to ferment a wide range of sugars, to grow autotrophically on H2/CO2, and more importantly on synthesis gas (H2/CO/CO2) make them very attractive candidates as production hosts for biofuels and biocommodities. Acetogenic metabolism is considered one of the earliest modes of bacterial metabolism. A thorough understanding of various factors governing the metabolism, in particular energy conservation mechanisms, is critical for metabolic… CONTINUE READING
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