Characterizing a Mammalian Circannual Pacemaker

@article{Lincoln2006CharacterizingAM,
  title={Characterizing a Mammalian Circannual Pacemaker},
  author={G. Lincoln and I. Clarke and R. Hut and D. Hazlerigg},
  journal={Science},
  year={2006},
  volume={314},
  pages={1941 - 1944}
}
Many species express endogenous cycles in physiology and behavior that allow anticipation of the seasons. The anatomical and cellular bases of these circannual rhythms have not been defined. Here, we provide strong evidence using an in vivo Soay sheep model that the circannual regulation of prolactin secretion, and its associated biology, derive from a pituitary-based timing mechanism. Circannual rhythm generation is seen as the product of the interaction between melatonin-regulated timer cells… Expand
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TLDR
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