Characterizing Microstructural Tissue Properties in Multiple Sclerosis with Diffusion MRI at 7 T and 3 T: The Impact of the Experimental Design

@article{Santis2018CharacterizingMT,
  title={Characterizing Microstructural Tissue Properties in Multiple Sclerosis with Diffusion MRI at 7 T and 3 T: The Impact of the Experimental Design},
  author={Silvia De Santis and Matteo Bastiani and Amgad Droby and Pierre Kolber and Frauke Zipp and Eberhard Daniel Pracht and Tony St{\"o}cker and Sergiu Groppa and Alard Roebroeck},
  journal={Neuroscience},
  year={2018}
}
The recent introduction of advanced magnetic resonance (MR) imaging techniques to characterize focal and global degeneration in multiple sclerosis (MS), like the Composite Hindered and Restricted Model of Diffusion, or CHARMED, diffusional kurtosis imaging (DKI) and Neurite Orientation Dispersion and Density Imaging (NODDI) made available new tools to image axonal pathology non-invasively in vivo. These methods already showed greater sensitivity and specificity compared to conventional… CONTINUE READING
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