Characterizing DNA methylation alterations from The Cancer Genome Atlas.

  title={Characterizing DNA methylation alterations from The Cancer Genome Atlas.},
  author={Daniel J. Weisenberger},
  journal={The Journal of clinical investigation},
  volume={124 1},
The Cancer Genome Atlas (TCGA) Research Network is an ambitious multi-institutional consortium effort aimed at characterizing sequence, copy number, gene (mRNA) expression, microRNA expression, and DNA methylation alterations in 30 cancer types. TCGA data have become an extraordinary resource for basic, translational, and clinical researchers and have the potential to shape cancer diagnostic and treatment strategies. DNA methylation changes are integral to all aspects of cancer genomics and… CONTINUE READING

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