Characterization of von Willebrand factor in primary pulmonary hypertension

@article{Collados1999CharacterizationOV,
  title={Characterization of von Willebrand factor in primary pulmonary hypertension},
  author={Mar{\'i}a Teresa Collados and Julio Sandoval and Sergio L{\'o}pez and Felipe A. Mass{\'o} and A. Paez and Jos{\'e} Rafael Borbolla and Luis Felipe Monta{\~n}o},
  journal={Heart and Vessels},
  year={1999},
  volume={14},
  pages={246-252}
}
The aim of this study was to determine the value of von Willebrand factor (vWF), a well-characterized endothelial cell protein secretion, as a marker for prognosis in patients with primary pulmonary hypertension (PPH). Venous and arterial blood samples were obtained from 18 clinically diagnosed PPH patients and 12 case controls matched for age and sex. Plasma vWF antigen was determined by enzymelinked immunosorbent assay (ELISA). The patients' multimeric vWF pattern was analyzed by sodium… CONTINUE READING

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