Characterization of voltage-sensitive sodium channel gene coding sequences from insecticide-susceptible and knockdown-resistant house fly strains.

@article{Ingles1996CharacterizationOV,
  title={Characterization of voltage-sensitive sodium channel gene coding sequences from insecticide-susceptible and knockdown-resistant house fly strains.},
  author={Patricia J. Ingles and Paul. M. Adams and Douglas C. Knipple and David M. Soderlund},
  journal={Insect biochemistry and molecular biology},
  year={1996},
  volume={26 4},
  pages={319-26}
}
The kdr insecticide resistance trait of the house fly (Musca domestica .L.), which confers reduced neuronal sensitivity to DDT and pyrethroid insecticides, was previously shown to exhibit tight genetic linkage to restriction fragment length polymorphism markers lying within a voltage-sensitive sodium channel gene that is homologous to the para gene of Drosophila melanogaster. In the present study, the 6315 nucleotide coding sequences of this voltage-sensitive sodium channel gene from… CONTINUE READING
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