Characterization of virulence plasmid diversity among Clostridium perfringens type B isolates.

@article{Sayeed2010CharacterizationOV,
  title={Characterization of virulence plasmid diversity among Clostridium perfringens type B isolates.},
  author={Sameera Sayeed and Jihong Li and Bruce A McClane},
  journal={Infection and immunity},
  year={2010},
  volume={78 1},
  pages={495-504}
}
The important veterinary pathogen Clostridium perfringens type B is unique for producing the two most lethal C. perfringens toxins, i.e., epsilon-toxin and beta-toxin. Our recent study (K. Miyamoto, J. Li, S. Sayeed, S. Akimoto, and B. A. McClane, J. Bacteriol. 190:7178-7188, 2008) showed that most, if not all, type B isolates carry a 65-kb epsilon-toxin-encoding plasmid. However, this epsilon-toxin plasmid did not possess the cpb gene encoding beta-toxin, suggesting that type B isolates carry… CONTINUE READING

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