Characterization of vinpocetine effects on DA and DOPAC release in striatal isolated nerve endings

@article{Trejo2001CharacterizationOV,
  title={Characterization of vinpocetine effects on DA and DOPAC release in striatal isolated nerve endings},
  author={Francisco Trejo and Vladimir Nekrassov and Marı́a Sitges},
  journal={Brain Research},
  year={2001},
  volume={909},
  pages={59-67}
}
Characterization of Phenytoin, Carbamazepine, Vinpocetine and Clorgyline Simultaneous Effects on Sodium Channels and Catecholamine Metabolism in Rat Striatal Nerve Endings
TLDR
Besides the antagonism exerted by carbamazepine, phenytoin and vinpocetine on excitatory neurotransmitters release triggered by Na+ channel activation, they exert different actions on striatal dopamine distribution, that might explain their different side effect profiles.
Vinpocetine blockade of sodium channels inhibits the rise in sodium and calcium induced by 4-aminopyridine in synaptosomes
Dihydropiridines Mechanism of Action in Striatal Isolated Nerve Endings: Comparison with ω-Agatoxin IVA
TLDR
It is concluded that the reduction in presynaptic Na+ channel permeability might contribute to the cerebral effects of DHPs.
Vinpocetine and α‐tocopherol prevent the increase in DA and oxidative stress induced by 3‐NPA in striatum isolated nerve endings
TLDR
The drop in DA produced by vinpocetine and α‐tocopherol may importantly contribute to their protective action from oxidative damage, particularly in DA‐rich structures.
Halothane enhances dopamine metabolism at presynaptic sites in a calcium-independent manner in rat striatum.
TLDR
The data suggest that halothane accelerates DA metabolism at presynaptic sites by releasing DA from reserpine-sensitive storage vesicles to the cytoplasm in a calcium-independent manner.
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