Characterization of variable immunodominant antigens of Cowdria ruminantium by ELISA and immunoblots.

@article{Perez1998CharacterizationOV,
  title={Characterization of variable immunodominant antigens of Cowdria ruminantium by ELISA and immunoblots.},
  author={Jeanne Mialet Perez and D. Martinez and Christian Sheikboudou and Frans Jongejan and Albert Bensaid},
  journal={Parasite immunology},
  year={1998},
  volume={20 12},
  pages={613-22}
}
Cross-immunization experiments have revealed a significant antigenic diversity of the isolate of Cowdria ruminantium which needs to be characterized for the development of vaccines. We identified polymorphic immunodominant antigens by ELISA and immunoblot. Using serum from a goat immune to the Gardel stock of Cowdria (isolated in Guadeloupe) adsorbed on antigen of the Senegal stock of this pathogen, distinct serogroups were revealed by ELISA among six isolates from different geographical… CONTINUE READING