Characterization of unique signature sequences in the divergent maternal protein Bcl2l10.

  title={Characterization of unique signature sequences in the divergent maternal protein Bcl2l10.},
  author={Yannis Guillemin and Aur{\'e}lie Cornut-Thibaut and Germain Gillet and François Penin and Abdel Aouacheria},
  journal={Molecular biology and evolution},
  volume={28 12},
Insertions or deletions (indels) of amino acids residues have been recognized as an important source of genetic and structural divergence between paralogous Bcl-2 family members. However, these signature sequences have not so far been extensively investigated amongst orthologous Bcl-2 family proteins. Bcl2l10 is an antiapoptotic member of the Bcl-2 family that has evolved rapidly throughout the vertebrate lineage and which shows conserved abundant expression in eggs and oocytes. In this paper… CONTINUE READING


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