Characterization of two polymorphic sites in the human kinin B1 receptor gene: altered frequency of an allele in patients with a history of end-stage renal failure.

@article{Bachvarov1998CharacterizationOT,
  title={Characterization of two polymorphic sites in the human kinin B1 receptor gene: altered frequency of an allele in patients with a history of end-stage renal failure.},
  author={Dimcho Bachvarov and Michelle R Landry and Isabelle Chantale Pelletier and Mario Chevrette and Christine B{\'e}tard and I Houde and Jean Bergeron and Michel Lebel and François Marceau},
  journal={Journal of the American Society of Nephrology : JASN},
  year={1998},
  volume={9 4},
  pages={598-604}
}
On the basis of the genomic structure of the human B1 receptor (B1R) for kinins, the presence of possible allelic polymorphisms of this gene was investigated using restriction fragment-length polymorphism and single-strand conformation polymorphism. The frequencies of the found alleles were determined in healthy volunteers and in patients with a history of end-stage renal failure, because there is evidence for a nephroprotective action of the kallikrein-kinin system. An A1098-->G polymorphism… CONTINUE READING

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Other investigators have mapped the bradykinin B2 receptor ( B2R ) gene to a close site on human chromosome 14 .
Other investigators have mapped the bradykinin B2 receptor ( B2R ) gene to a close site on human chromosome 14 .
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