Characterization of two highly metastatic variants of Lewis lung carcinoma with different organ specificities.

  title={Characterization of two highly metastatic variants of Lewis lung carcinoma with different organ specificities.},
  author={Pnina Brodt},
  journal={Cancer research},
  volume={46 5},
The biological properties and metastasis of two sublines of the Lewis lung carcinoma (3LL) which have maintained a stable pattern of organ-selective metastasis have been studied. Subline M-3LL, a lung-specific variant which originated from a lung metastasis of the parent line, metastasized only to the lung following injection of 10(4)-10(6) tumor cells i.v. or s.c. Lymphatic metastases of this tumor were rarely detected. Subline H-3LL which was developed from a rare, spontaneous hepatic… CONTINUE READING


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