Characterization of two functional glucocorticoid receptors in the marine medaka Oryzias dancena.

@article{Kim2011CharacterizationOT,
  title={Characterization of two functional glucocorticoid receptors in the marine medaka Oryzias dancena.},
  author={Mi Ae Kim and Dong Soo Kim and Young Chang Sohn},
  journal={General and comparative endocrinology},
  year={2011},
  volume={171 3},
  pages={
          341-9
        }
}
The cDNAs that encode the glucocorticoid receptors odGR1 and odGR2 were cloned from a euryhaline teleost, the marine medaka (Oryzias dancena). The open reading frames of odGR1 and odGR2 encode 790 and 783 amino acids, respectively, and show a sequence identity of 46% with each other. When inter- and intra-species comparisons of the GR domains were made, the N-terminal AF-1 (A/B) and hinge (D) domains showed relatively low identities, whereas the DNA-binding (C) domain (DBD) and ligand-binding… CONTINUE READING
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